Salicylic acid - Hormone Synthetic Pathways and Genes in Arabidopsis

Salicylic acid (SA)

The production of salicylic acid in plants is associated with disease resistance. Salicylic acid induces the accumulation of pathogenesis-related (PR) proteins in a variety of plants. Salicylic acid biosynthesis was initially studied biochemically in tobacco leaves and a benzoic acid-dependent route has been discovered. More recent work using Arabidopsis mutants suggested that the isochorismate-dependent pathway is likely to be predominant in this species, which has been established for salicylic acid biosynthesis in some bacteria genera. The SA biosynthesis pathway through isochorismate in Arabidopsis is shown here.

Genes on the pathway

Gene name Locus name Description
ICS1/SID2 At1g74710 isochorismate synthase
ICS2 At1g18870 isochorismate synthase
BSMT1 At3g11480 benzoic acid/salicylic acid carboxyl methyltransferase
UGT74F1 At2g43840 salicylic acid glucosyltransferase
UGT74F2 At2g43820 salicylic acid glucosyltransferase
AtMES1 At2g23620 methyl salicylate esterase
AtMES2 At2g23600 methyl salicylate esterase
AtMES7 At2g23560 methyl salicylate esterase
AtMES9 At4g37150 methyl salicylate esterase
RIKEN Plant Hormone Research Network - RIKEN Center for Sustainable Resource Science